As far as cosmologists can tell, there were only three elements present when the universe was first formed some 13.8 billion years ago: hydrogen, helium, and lithium. Vote Now, Melania Trump's Christmas Decorations Gave the Internet the Most Wonderful Memes of the Year, You can unsubscribe at any time. There were no significant differences in the rate of attrition, discontinuation due to all causes or adverse events, or CSF biomarkers between treatment groups. In fact, 7UP was originally called "Bib-Label Lithiated Lemon-Lime Soda" when it was created all the way back in 1929. The “up” supposedly is the uplift that you got from the lithium in there and the “seven” they said that contains seven ingredients. “Bib-Label Lithiated Lemon-Lime Sodas” contained the compound lithium citrate, a mood-stabilizing drug, used in various patent medicines at the time. When 7Up was first sold, it was produced in 7-ounce bottles. There is extensive pharmacology of lithium, the active component of this salt.. Lithia water contains various lithium salts, including the citrate. In fact, the fizzy drink was originally known as “Bib-Label Lithiated Lemon-Lime Soda,” according to the Huffington Post. 7 Up (stylized as 7up outside the U.S.) is an American brand of lemon-lime-flavored non-caffeinated soft drink.The rights to the brand are held by Keurig Dr Pepper in the United States and by 7 Up international in the rest of the world. Why 7UP? 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When it was initially released, the lemon-lime soda that we know as 7-Up was clumsily called Bib-Label Lithiated Lemon-Lime Soda. It was popular to go to lithium-containing springs such as Lithia Springs, Georgia or Ashland, Oregon for this effect. Of course, the mind-altering substance was removed from the drink when the U.S. Food and Drug Administration outlawed the use of the chemical in soda in 1948. 7-UP was not the only soft drink to have its original formula contain a drug. Lithi… Lithium has to reach a certain level in your blood before it has therapeutic effects, and people who take Lithium for bipolar need to take the drug for days to weeks before it reaches the therapeutic dose. Using data for 27 Texas counties from 1978-1987, it is shown that the incidence rates of suicide, homicide, and rape are significantly higher in counties whose drinking water supplies contain little or no lithium than in counties with water lithium levels ranging from 70-170 micrograms/L; the differences remain statistically significant (p less than 0.01) after corrections for population … It was even marketed and named Bib-Label Lithiated Lemon-Lime Soda. Originally called "Bib-Label Lithiated Lemon-Lime Soda," the soft drink was marketed in the late-19th and early-20th centuries as a health drink due to containing lithium. In the clip, Sir Martyn Poliakoff, a chemistry professor at the University of Nottingham, explains what happened when his colleagues placed a piece of lithium inside a beaker containing the beverage. The U.S. Food and Drug Administration banned the use of lithium in beer and soft drinks in 1948, and 7-Up was reformulated two years later. 7 Up sign, Sleepy Dog House, Bisbee, Arizona. Lithium citrate is considered a drug. (Maybe the “Up” referred to mood?).”. When it was released for sale in 1929, only a few weeks before the stock market crash that signaled the beginning of the Great Depression, 7Up contained lithium. First cre-ated by Charles Leiper Grigg of St. Louis in 1929 un-der the name of “Bib-Label Lithiated Lemon-Lime Soda,” it was originally formulated with lithium citrate 5  The ingredient was removed by 1950. Grigg died on April 16, 1940, and his son took command of the company. Several theories exist about its origin: 7Up was the product of seven ingredients. At the time, Orange Crush dominated the market for orange sodas, so Grigg decided to focus on lemon-lime flavors and came up with the formula for a lemon-lime soft drink in 1929. Use of this site constitutes acceptance of our, These Amazing Chemical Reactions Will Show You the True Beauty of Science, Here's the Gross Thing That Happens When You Mix 7-Up With Lithium. concentrations of lithium ion, he failed to mention one of the more famous commercial soft drinks that tried to cash in on the original lithium craze - 7 Up. There's some controversy about that. In a column published in The New York Times, Cornell University professor Anna Fels wrote: “Lithium drinks were in huge demand for their reputed health-giving properties, so much so that the element was added to commercial drinks. Some even believe the "7" in 7UP refers to the atomic mass of lithium, although it could just be in reference to the drink's original seven ingredients. The original recipe of 7Up contained just seven ingredients: sugar, carbonated water, essence of lemon and lime oils, citric acid, sodium citrate, and lithium citrate. Lithium citrate was the salt form of lithium in the 7-up recipe according to a number of sources including the Wikipedia: The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. Lithium citrate has been used for many decades for psychiatric treatment of manic states and bipolar disorder and as a supposed cure for hangovers at the time. This variation is sustained by an earlier 7UP tagline: “Seven natural tastes blended as a savory, flavory beverage with an actual wallop.” The seven components were carbonated water, sugar citric acid, lithium citrate, salt citrate, and essences of lemon and lime oils (technically two components). Lithium is used in batteries, ceramics, air-conditioning, grease, electric cars, and in pharmaceutical products. In 1817, Johan August Arfvedson of Stockholm analysed it and deduced it contained a previously unknown metal, which he called lithium. 7-Up was originally called Bib-Label Lithiated Lemon-Lime Soda and contained lithium citrate right up until 1950. On earth, lithium remains a major mineral component of granite rock, and also lingers in significant amounts in sea water, mineral springs, and soils. The lithium reference comes from the inclusion of the mood-stabilizer in the recipe before its removal in the late 1940s. Grigg never explained the name, but he did promote 7UP as having effects on mood. In these disorders, it reduces the risk of suicide. Sign up to receive the top stories you need to know now on politics, health and more, © 2020 TIME USA, LLC. Charles Leiper Grigg was born on May 11, 1868, in Price’s Branch, Missouri. February 20, 2016 2:14 PM EST W hen 7-Up was first invented, one of its ingredients was lithium salts. It actually used lithium citrate, a mood-stabilizing drug, in … He invented his first soft drink called “Whistle” while he was working for a manufacturing company owned by Vess Jones, but after a conflict with the management, he left the company. Lithium was first prescribed for mania in 1871 by William Hammond, professor of Diseases of the Mind and Nervous System at the Bellevue Hospital Medical College in New York; next, in 1894, Danish psychiatrist Frederik Lange made explicit reference to lithium in the treatment of melancholic depression. Lithium citrate (Li 3 C 6 H 5 O 7) is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder. The amount of lithium in the drinking water varies from place to place on this planet. Write to Megan McCluskey at megan.mccluskey@time.com. Leaving it in the 7-up (which was originally marketed as a hangover cure; actually most soft drinks started as some sort of pharmaceutical concoction: Dr Pepper; Coca-Cola, Pepsi) would have implied that it was not a soft drink, but something that requires a MD's prescription to get. Grigg never explained how he came up with the cryptic name. While the recipe no longer includes any form of psychiatric drugs, many 7Up fans point to its refreshing flavor and texture as the reason for its long-time popularity. When 7-Up was first invented, one of its ingredients was lithium salts. He moved to St. Louis when he was 22-years-old and started working in advertising and sales for soft drink companies. In fact, lithium was so popular as a health supplement before 1940 that 2 U.S. presidents had it shipped to the white house, and it was added as an ingredient to beer and soda. When 7-Up was created in 1929 it contained lithium, a mood-stabilizing drug Jan 16, 2017 Goran Blazeski Charles Leiper Grigg was born on May 11, 1868, in Price’s Branch, Missouri. Lithium is a soft, silver-white alkali metal, found in some foods and, in some places, the drinking water. The original formula for 7UP contained lithium citrate, a chemical used today as a treatment for bipolar disorders. It's a shame 7UP no longer contains lithium. The U.S. version of the 7 Up logo includes a red circle between the "7" and "Up"; this red circle has been animated and used as a mascot for the brand … In the century before Kurt Cobain’s moody ode to the soporific effect of medical-grade lithium, people flocked to natural springs where the element was abundant, Fels reports. The beverage was a patent medicine marketed as a cure for hangover. The government banned the use of Lithium citrate in soft drinks in 1948 and it was removed from 7-Up. As to why “7Up,” C.L. The therapeutic benefits of lithium are the reason it was first used in 7Up. The popular soda 7-UP used to contain lithium citrate, a mood-stabilizing drug used today to treat people with bipolar disorder. By signing up you are agreeing to our. Although some people suggested that maybe it referred to the number of times you burped after drinking the beverage. 7UP was originally marketed as a “lithiated soda” and the reason it’s called 7UP is that lithium’s molecular weight is 7. Lithium is one of the elements with an atomic number of seven, which some have proposed as a theory for why 7UP has its name. He changed the name of his company from “Howdy” to “The Seven Up Corporation” and by the 1940s, 7-Up was the third best-selling soft drink in the world. Lithium compounds, also known as lithium salts, are primarily used as a psychiatric medication. Grigg claimed that the Lithia ingredient in the soda could affect the drinker’s moods. In 1871, William Hammond, professor of Diseases of the Mind and Nervous System at the Bellevue Hospital Medical College in New York, became the first physician to prescribe lithium for mania; in 1894, Danish psychiatrist Frederik Lange made explicit reference to lithium in the treatment of melancholic depression. Because it debuted at the time of the stock market crash of 1929 and the onset of the Great Depression, this was a selling point. Lithium … Lithium significantly decreased cognitive decline as compared to placebo (standardized mean difference = -0.41, 95% confidence interval = -0.81 to -0.02, p = 0.04, I2 = 47% , 3 studies, n = 199). Lithium in 7UP "The original formulation contained lithium citrate, which was used in various patent medicines at the times for improving moods. Lithium Orotate: Once Used In 7up Now Treats Bipolar Disorder A lithium orotate beverage was marketed as “lithiated lemon soda” in the mid 1900s, apparently to make it seem healthier but eventually it was stated as poisonous and the FDA had to get involved. The original formula included the mood-stabilizing drug lithium citrate in its formula, which is still used to treat bipolar disorder and other mood disorders to this day (via Gizmodo). He found a job at a new soft drink manufacturer where he invented another orange-flavored drink called “Howdy.” He went on to form the Howdy Company together with financier Edmund G. Ridgway, and lawyer Frank Gladney. 7UP was originally named 'Bib-Label Lithiated Lemon-Lime Soda' and contained lithium citrate, a mood-enhancing drug, until its use in soft drinks was banned in 1948 There are many theories as to where the 7UP takes its name from. He moved to St. Louis when he was 22-years-old and started working in advertising and sales for soft drink companies. Chris Barnes, a spokesman for the Dr. Pepper Snapple Group -- the beverage behemoth to which 7-Up was sold in 1986 (before that, it changed hands from its founder to tobacco giant Philip Morris, interestingly) - said Grigg took the secret behind … Here is another story from us: The British were selling about 1,400 tons of opium per year to China, which eventually led to the Opium War. Save on the cover price & free e-Gift card for Giftees! Photo Credit. Lithium is in the alkali-metal group that includes sodium and potassium. All Rights Reserved. It was on the basis of lithium’s salubrious reputation that it was added to Bib-Label Lithiated Lemon-Lime Soda—or what would become 7-Up. According to Japanese-German research that has been published in the European Journal of Nutrition, people live a little longer if their drinking water contains more lithium. The sun, stars, and meteorites burn brightly with the flame of this highly reactive element. The mixture quickly began to heat up, boil, and change color, finally resulting in a black alkaline goo. In fact, it’s been suggested that the 7 in 7-Up refers to the atomic mass of the lithium. Back then, lithium was considered a beneficial mood enhancer, which is where the “Up” aspect of the name comes in. There were around 600 other lemon-lime sodas, but the new drink actually sold pretty well. As one of the three original elements, lithium is found throughout our atmosphere. However, the team over at Periodic Videos recently decided to test what would happen if they tried to add lithium back into 7-Up. Will Coronavirus's Disruption of Big Ag Have Lasting Change? Grigg shortened the name to “7-Up Lithiated Lemon-Lime” and eventually just called it 7-Up. Lithium is one of the elements… The first lithium mineral petalite, LiAlSi 4 O 10, was discovered on the Swedish island of Utö by the Brazilian, Jozé Bonifácio de Andralda e Silva in the 1790s.It was observed to give an intense crimson flame when thrown onto a fire. Way back in the day, 7Up had lithium in it.So, the chemistry department at the University of Nottingham decided to have a little fun and see if they could put the lithium back into the 7Up. What Donald Trump Can — And Can't — Do with the Pardon Power, Who Should Be TIME’s Person of the Year for 2020? It is primarily used to treat bipolar disorder and treat major depressive disorder that does not improve following the use of antidepressants. Read More: These Amazing Chemical Reactions Will Show You the True Beauty of Science.
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